7 jun. Rabdomiólise, uma palavra que é muito importante no mundo dos “gymmers”. Sabe porquê? Trata-se de uma síndrome grave provocada pelo. Rhabdomyolysis is a process of muscle destruction that can present with varying clinical manifestations. In pediatric patients, its main etiology is infectious. Esse relato descreve o caso de uma mulher com lúpus eritematoso sistêmico ( LES) que sofreu rabdomiólise em seguida à sua infecção pelo vírus da dengue.
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Trauma-related events that are particularly likely to lead to rhabdomyolysis include the following:.
Sabe o que é a rabdomiólise?
Its final common pathway may be a disturbance in myocyte calcium homeostasis. The following initial settings were used: A calcium antagonist was prescribed on day six due to worsening hypertension.
Fasciotomy is the incision of the affected compartment. Initially this is done through the administration of generous amounts of intravenous fluidsusually isotonic saline 0. Excess myoglobin may thus cause renal tubular obstruction, direct nephrotoxicity ischemia and tubular injuryintrarenal vasoconstriction, and acute kidney injury AKI.
Salluzzo R, Schwartz M. Francisella tularensis [ 1424 ]. She was the only child of non-consanguineous parents. There are only a few cases of SLE accompanied by rhabdomyolysis, none of rabdomiolkse associated with dengue fever. Archived from the original on 8 September Management of crush-related injuries after disasters.
Rhabdomyolysis following recent severe coxsackie virus infection in rabdmiolise with chronic renal failure: Efficacy and safety of statin therapy in children with familial hypercholesterolemia: Mycoplasma pneumoniae–associated transverse myelitis and rhabdomyolysis. The prevalence of false-positive cardiac troponin I in ED patients with rhabdomyolysis. Author links open overlay panel Louise D. According to a retrospective analysis of FDA records[ 43 ] the most commonly suspected drug exposure in children younger than 10 years was propofol.
E – Amadora, Portugal. Arterial thrombosis blood clots forming locally or embolism clots or rabodmiolise debris from elsewhere in the bodyclamping of an artery during surgery  . AKI rarely occurs in patients with chronic myopathies unless it is triggered by a second inciting event.
Rhabdomyolysis as a manifestation of a metabolic disease: a case report
Although currently VLCAD deficiency is mainly diagnosed with the newborn screening card that has allowed for earlier diagnosis, different methods can be used for its diagnosis, such as chromatographic analysis of plasma fatty acids, tandem mass spectrometry analysis of acylcarnitines and organic acids analysis in urine. Other complications of rhabdomyolysis, such as compartment syndrome, should be monitored, and surgical decompression should be performed as soon as needed.
A comparable figure in children is unavailable. Gastrointestinal GI ischemia is common in patients with fluid and electrolyte imbalances. Cold exposure in addition to heatstroke is an environmental cause of rhabdomyolysis. Rhabdomyolysis induced by rsbdomiolise caffeine overdose. Archived from the original on 9 August The positive dengue serology was only available after the therapy above had been established.
Barry L Myones, MD is a member of the following medical societies: The spectrum of rhabdomyolysis. The major therapeutic interventions in rhabdomyolysis are conservative.
Rhabdomyolysis has many etiologies and is often multifactorial in adult radomiolise. See Presentation for more detail. Treatment consists of diet modifications and should include a diet low in very long-chain fatty acids with supplements of medium-chain triglycerides.
Rhabdomyolysis may cause kidney failure by several mechanisms.
Schwengel D, Ludwig S. Prolonged immobilization eg, after excess alcohol rabromiolise drug consumption, after an unwitnessed incapacitating stroke, or after prolonged surgical procedures. A diagnosis of rhabdomyolysis may be suspected in anyone who has suffered trauma, crush injury or prolonged immobilization, rabdomoilise it may also be identified at a later stage due to deteriorating kidney function abnormally raised or increasing creatinine and urea levels, falling urine output or reddish-brown discoloration of the urine.
At presentation, she was dehydrated.
Views Read Edit View history. HIV infection and rheumatic diseases: Archived from the original on 15 January New risk score predicts outcome in rhabdomyolysis. The swelling itself may lead to destruction of muscle cells, but those cells that survive are subject to various disruptions that lead to rise in intracellular calcium ions; the accumulation of calcium outside the sarcoplasmic reticulum leads to continuous muscle contraction and depletion of ATPthe main carrier of energy in the cell.
Although there is no clear clinical evidence for its effectiveness, a forced alkaline diuresis may be performed with bicarbonate administration in order to reduce the renal toxicity of heme.